Melatonin Plus
with Chamomile & Valerian
We're sorry! This item is discontinued and is no longer available.
Pure Melatonin imported from Switzerland provides Natural Seratonin and Other Natural Hormones.
This exclusive formula from Vitamin Power supplies valuable additional nutrients including Pantothenic Acid, Calcium, and Magnesium.
WARNINGS: Take only at bedtime. Do not exceed recommended dosage. Should not be used in these conditions: Pregnancy and lactation, autoimmune disorders, depression or use of anti-depressants, endocrine disorder or diabetes. Do not drive or operate heavy machinery after use.
Find Melatonin Sleep Aid Supplements at a Featured Merchant (below)
| Each Tablet Contains | |
| Melatonin (N-Acetyl-5-Methoxytryptamine) | 600 mcg |
| Pantothenic Acid (Calcium Pantothenate) |
10 mg |
| Calcium (Carbonate) | 100 mg |
| Magnesium (Gluconate) | 50 mg |
| Chamomile (finely-milled herb flower) |
50 mg |
| Valerian (finely-milled herb root) | 100 mg |
No Sugar, Starch, Salt, Artificial Colorings, Flavorings or preservatives.
Low Melatonin Increases Risk of Breast Cancer
Low Melatonin levels are associated with an increased risk of breast cancer in postmenopausal women, according to a prospective case-control study.
Melatonin is naturally secreted in the body during the dark hours of a light-dark cycle and has been shown to be low in some night workers.
Researchers have found that low Melatonin levels in premenopausal women are associated with an increased risk of breast cancer. To find out if a similar association occurs in postmenopausal women, a research team of the Brigham and Women's Hospital and Harvard Medical School in Boston compared melatonin levels in 178 postmenopausal women and 710 matched controls. All of the women were enrolled in the prospective Hormones and Diet in the Etiology of Breast Cancer Risk study.
The researchers found that women with the lowest levels of Melatonin had a statistically significantly higher incidence of breast cancer than those with the highest levels.
The researchers conclude that low Melatonin levels are associated with an increased risk of breast cancer. Further studies need to confirm these data and should investigate the mechanisms that underlie the association.
This research was recently published in the Journal of the National Cancer Institute.
Melatonin is a hormone supplement that helps regulate sleep patterns.
Tests were done on a small group of blind people having a high occurrence of sleep disorders at the Oregon Health Sciences University because not being able to see the daily cycle of light and dark interferes with peoples' biological clock.
The study found that normal sleep patterns occurred in nearly all the subjects after having them take melatonin. The subjects that received a placebo continued to experience sleep disorders. The results were published in the New England Journal of Medicine.
New Study Indicates Melatonin May Be Useful For Helping Prevent Cirrhosis of the Liver, As An Anti-Fibrotic Drug
In China, the incidence of liver cirrhosis is still high. Liver cirrhosis results from fibrosis. If treated properly at fibrosis stage, cirrhosis can be prevented. However, no effective antifibrosis drugs are presently available.
Several studies have shown evidence suggesting that oxidative stress plays an important role in the etiopathogenesis of hepatic fibrosis.
Melatonin can protect cells, tissues, and organs against oxidative damage induced by a variety of free-radical-generating agents and processes.
A research team from the First Affiliated Hospital of Anhui Medical University, China evaluated the possible beneficial fibrosuppressant effect of Melatonin in several controlled laboratory experiments.
In this new study, hepatic fibrosis in laboratory mice was induced by subcutaneous injection of sterile CCl4 twice weekly for a total of 12 wk. At the beginning of injection of CCl4, Melatonin (2.5, 5, 10 mg/kg body weight) was administered daily, for a total of 12 weeks.
Hepatic fibrotic changes were evaluated biochemically by measuring tissue hydroxyproline levels and histopathogical examination. The serum levels and activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST) were used to evaluate the hepatic injury. Hepatic oxidative stress markers were evaluated by changes in the amount of lipid peroxides, measured as malondialdehyde (MDA) and glutathione peroxidase (GPx) in liver homogenates. Serum hyaluronic acid (HA), laminin (LN), and procollagen 3 N-terminal peptide (P3NP) were determined as serum markers of hepatic fibrogenesis
The results suggested that treatment with Melatonin (10 mg/kg) could decrease the scores of hepatic fibrosis grading, reduced the contents of HA, LN in serum and Hydroxyproline (HYP) in liver, treatment with Melatonin (5,10 mg/kg ) could decrease serum levels of ALT, AST and blocked the increase in MDA in subjects with hepatic injury caused by CCl4.
Their results indicated Melatonin could improve CCl4-induced hepatic fibrosis in laboratory mice. The beneficial, protective effect of Melatonin on hepatic fibrosis may be related to its powerful antioxidant activities. This study may provide a basis for further studies on the potentially protective effect of Melatonin on liver function in cirrhotic patients.
Melatonin Is An Effective Treatment For Sleep Problems In Children With Autism, Study Suggests
A new study determined that over-the-counter Melatonin supplements can reduce the length of time it takes for children with autistic spectrum disorder (ASD), Fragile X Syndrome (FXS), or both to fall asleep at the beginning of the night.
Results of the study indicated that children who received Melatonin treatments experienced significant improvements in total night sleep durations, sleep latency times, and sleep-onset times. Mean sleep duration was longer on Melatonin than placebo by 21 minutes, sleep-onset latency was shorter by 28 minutes and sleep-onset time was earlier by 42 minutes.
According to the sudy conducted at the M.I.N.D Institute at the University of California Davis Health System in Sacramento, California, treatment with over-the-counter Melatonin supplements benefits children of all ages, which helps alleviate some of the additional stress that parents of special-needs children experience because sleep onset problems at the beginning of the night are very troublesome for children and their families. Sometimes children may take one to two hours to fall asleep and often they disrupt the household during this time.
Dyssomnia is defined as difficulty falling asleep and frequent nighttime awakenings, among the most commonly reported problems. Researchers hypothesize that difficulty sleeping in these children is increased due to abnormal levels of Melatonin, a natural hormone secreted from the pineal gland that is believed to promote sleep at night.
The study included information from 12 children between the ages of 2 to 15 years. Sleep quality and quantity were measured both objectively and subjectively. Five participants met diagnostic criteria for autism, 3 for FXS, 3 for FXS and ASD, and 1 for FXS alone.
Participants were given two weeks' supply of either Melatonin or a placebo. After they completed the two week dosage they were then crossed over to the alternate treatment for an additional two weeks. All participants were assessed for autism and received DNA testing for the diagnosis of FXS.
Authors recommend that in addition to the use of over-the-counter Melatonin supplements, behavior therapies and sleep hygiene practices should be used to manage sleep problems in children with autism and FXS.
Journal reference: The Efficacy of Melatonin for Sleep Problems in Children with Autism, Fragile X Syndrome, or Autism and Fragile X Syndrome. Journal of Clinical Sleep Medicine, April 15, 2009.
